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New Practical Synthesis of Tetrahydronquinolin-2,5-diones
Authors:XIA De-xing  FENG Chun  WANG Qiu-yan  LU Cui-fen  CHEN Zu-xing and YANG Gui-chun
Institution:Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Ministry of Education, School of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, P. R. China
Abstract:A series of 4,6,7,8-tetrahydro-2,5-(1H,3H)-quinolinediones was prepared from ethyl-2-cyanoacetate, aromatic aldehydes and 1,3-cyclohexanedione or 5,5-dimethyl-1,3-cyclohexanedione by two steps, the yields were moderate to excellent. This method is a new practical promising green strategy to synthesize tetrahydronquino-lin-2,5-diones.
Keywords:Tetrahydrobenzo[b]pyran  Tetrahydronquinolin-2  5-dione  Synthesis  
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