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A convenient synthesis of 6-demethoxycapillarisin
引用本文:Yuan Feng Tong Shuai Chen Yong Hao Cheng Song Wu. A convenient synthesis of 6-demethoxycapillarisin[J]. 中国化学快报, 2007, 18(4): 407-408. DOI: 10.1016/j.cclet.2007.01.049
作者姓名:Yuan Feng Tong Shuai Chen Yong Hao Cheng Song Wu
作者单位:Yuan Feng Tong,Shuai Chen,Yong Hao Cheng,Song Wu* Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China
摘    要:A convenient and effective method for the synthesis of 6-demethoxycapillarisin was described.The highlight was involved in asimple access to the key intermediate 2-ethylthio-5,7-dimethoxy-4H-chromen-4-one from the inexpensive 2,4,6-trihydroxyacetophenone,using AlCl3 as the demethylation reagent.

关 键 词:6-去甲氧基茵陈色原酮 合成方法 苯并-γ-吡喃酮 脱甲基化试剂

A convenient synthesis of 6-demethoxycapillarisin
Yuan Feng Tong,Shuai Chen,Yong Hao Cheng,Song Wu. A convenient synthesis of 6-demethoxycapillarisin[J]. Chinese Chemical Letters, 2007, 18(4): 407-408. DOI: 10.1016/j.cclet.2007.01.049
Authors:Yuan Feng Tong  Shuai Chen  Yong Hao Cheng  Song Wu
Affiliation:Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Abstract:A convenient and effective method for the synthesis of 6-demethoxycapillarisin was described.The highlight was involved in a simple access to the key intermediate 2-ethylthio-5,7-dimethoxy-4H-chromen-4-one from the inexpensive 2,4,6-trihydroxyacetophenone,using AlCl3 as the demethylation reagent.
Keywords:Synthesis  6-Demethoxycapillarisin  Chromone
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