Cladieunicellins A-E, new eunicellins from an Indonesian soft coral Cladiella sp |
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| Authors: | Chen Yung-Husan Tai Chia-Ying Kuo Yueh-Hsiung Kao Chia-Ying Li Jan-Jung Hwang Tsong-Long Fang Lee-Shing Wang Wei-Hsien Sheu Jyh-Horng Sung Ping-Jyun |
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| Institution: | National Museum of Marine Biology and Aquarium, Pingtung, Taiwan. |
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| Abstract: | Five new eunicellin-type diterpenoids, cladieunicellins A-E (1-5), were isolated from an Indonesian soft coral identified as Cladiella sp. The structures of diterpenoids 1-5 were established using spectroscopic methods. Eunicellins 2 and 5 were found to be cytotoxic against DLD-1 and HL-60 tumor cells, respectively, and 3 displayed inhibitory effects against superoxide anion generation by human neutrophils. |
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