Straightforward solvent-free synthesis of new chiral benzene-1,3,5-tricarboxamides |
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| Authors: | Guadalupe Hernández Manju Sharma Pankaj Sharma Oscar Portillo Alejandro Ruiz |
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| Institution: | 1. Laboratorio de Síntesis de Complejos, Facultad de Ciencias Químicas, Universidad Autónoma de Puebla, Puebla, México;2. Ingeniería Bioquímica, Instituto Tecnológico Superior de Atlixco, Atlixco, Puebla, México;3. Instituto de Química, UNAM, México, D.F, México;4. Departamento de Microbiología, Facultad de Ciencias Químicas, Universidad Autónoma de Puebla, Puebla, México |
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| Abstract: | A new series of chiral benzene-1,3,5-tricarboxamides (BTAs) 3a–e was prepared using the ecofriendly solvent-free approach, starting with benzene-1,3,5-tricarbonyl chloride 1 and appropriate optically pure primary amines 2a–e. All the reactions occur in a short time with excellent yields (>90%). The structures of the compounds have been characterized by Fourier transform infrared spectroscopy (FT–IR), Proton nuclear magnetic resonance (1H NMR), Carbon 13 nuclear magnetic resonance (13C NMR), electron ionization mass spectrometry (EI–MS), and elemental analysis. |
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| Keywords: | solvent-free chiral C3-symmetric ligands benzene-1 3 5-tricarboxamides |
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