| β-Cyclodextrin Enhanced Fluorimetric Method for Determination of Amoxicillin in Dosage |
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| 基金项目： | Supported by the National Natural Science Foundation of China(No.40973081); the Foundation for Analysis and Measurement of Kunming University of Science and Technology, China(No.2009092); the Innovation Fund for Small Technology Based Firms, China (No.10C26215305131) |
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| 摘 要： | A simple sensitive spectrofluorimetric method was developed for the determination of amoxicillin. Amoxicillin in the presence of formaldehyde produces a fluorescent pyrazine derivative, whose fluorescence intensity can be enhanced by forming an inclusion complex with β-cyclodextrin. Optimum conditions for the determination of amoxicillin were also investigated. Fluorimetric detection was carried out at λex=365 nm and λem=445 nm. The linear range of this method for the determination of amoxicillin is 0.1―10 ...
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| 关 键 词： | Fluorescence Amoxicillin β-Cyclodextrin Inclusion complex |
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