Synthesis and Drug Release Properties of Thermosensitive Poly(N-vinylacetamide-co-vinylacetate) Hydrogels |
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| Authors: | YANG Li-he CHU Hong CHEN Ming-qing HU Na ZHAO Yi-fan School of Chemical Material Engineering Jiangnan University Wuxi P. R. China |
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| Affiliation: | YANG Li-he,CHU Hong,CHEN Ming-qing*,HU Na and ZHAO Yi-fan School of Chemical and Material Engineering,Jiangnan University,Wuxi 214122,P. R. China |
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| Abstract: | Thermosensitive poly[N-vinylacetamide-co-vinylacetate][P(NVA-co-VAc)] hydrogels were prepared via free radical copolymerization from hydrophilic NVA and hydrophobic VAc in the presence of butylenes-bis (N-vinylacetamide)(Bis-NVA) as crosslinker. Scanning electron microscopy(SEM) images reveal that the as-prepared hydrogels were of three-dimensional network with irregular cave structure. The prepared hydrogels with more NVA in the feed swelled faster and the swelling ratio of the hydrogels gradually decrease... |
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| Keywords: | Poly(N-vinylacetamide-co-vinylacetate) Thermosensitive hydrogel Drug release |
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