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Simple lab-on-chip approach with time-based detection |
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| Authors: | K. Grudpan S. Lapanantnoppakhun S. Kradtap Hartwell K. Watla-iad W. Siriangkhawut W. Kumutanat S. Tontrong |
| Affiliation: | a Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand b Department of Chemistry, School of Science, Mae Fah Laung University, Chiang Rai 57100, Thailand c Institute for Science and Technology Research and Development, Chiang Mai University, Chiang Mai 50200, Thailand |
| Abstract: | A simple lab-on-chip approach with time-based detection is proposed. A platform is made from a piece of acrylic differently shaped channels for introducing sample and reagent(s) using flow manipulation. Time-based changes involving migration of the reaction zone are monitored. The changes can be visually monitored by using a stop-watch with naked eyes observation. Some applications for the determination of ascorbic acid, acetic acid and iron in real samples with different chemistries were demonstrated. |
| Keywords: | Lab-on-chip Time-based detection Ascorbic acid assay Acetic acid Iron determination Cost-effective analysis Migration time Visual detection |
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