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Neutron activation analysis for determination of metal ions in biological fluids of patients after CoCrMo arthroplasty
Authors:Noli  Fotini  Papadopoulos  Pavlos  Kolias  Pavlos  Tsiridis  Eleftherios  Papavasiliou  Kyriakos  Sayegh  Fares
Institution:1.Department of Chemistry, Aristotle University, 54124, Thessaloníki, Greece
;2.Academic Orthopaedic Unit, Papageorgiou General Hospital, Aristotle University Medical School, Thessaloníki, Greece
;3.Department of Mathematics, Aristotle University, 54124, Thessaloníki, Greece
;4.Centre of Orthopaedics and Regenerative Medicine (C.O.R.E.) - Centre of Interdisciplinary Research and Innovation (C.I.R.I.), Aristotle University, Thessaloníki, Greece
;
Abstract:

Determination of metals and trace elements in patients with total knee or hip arthroplasty with CoCrMo alloy was performed. Blood, urine and cerebrospinal fluid (CSF) samples were analyzed and compared with samples from healthy people. Levels of Co, Cr as well as Na, Ca, Fe, Zn, Se, Rb, Sb and Br were determined by means of neutron activation analysis. The values of Cr and Co of the blood and urine measurements were elevated in patients with replacement, and according to the statistical analysis, significant differences of the elements Zn, Br, Co and Sb were found in the CSF (p?<?0.05).

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