|
|||||
|
|
Design,synthesis, in vivo and in vitro studies of 1,2,3,4-tetrahydro-9H-carbazole derivatives,highly selective and potent butyrylcholinesterase inhibitors |
|
| Authors: | Ghobadian Roshanak Esfandyari Roghaieh Nadri Hamid Moradi Alireza Mahdavi Mohammad Akbarzadeh Tahmineh Khaleghzadeh-Ahangar Hossein Edraki Najmeh Sharifzadeh Mohammad Amini Mohsen |
| Affiliation: | 1.Department of Medicinal Chemistry, Faculty of Pharmacy, and Drug Design & Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran ;2.Pharmaceutical Science Research Center and Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, 8915173143, Iran ;3.Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran ;4.Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran ;5.Department of Physiology, School of Medicine, Babol University of Medical Sciences, Babol, Iran ;6.Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran ;7.Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran ; |
| Abstract: | Molecular Diversity - Inhibition of butyrylcholinesterase (BChE) might be a useful therapeutic target for Alzheimer’s disease (AD). A new series of 1,2,3,4-tetrahydro-9H-carbazole derivatives... |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |