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Synthesis and biological evaluation of 1,2,4-triazolidine-3-thiones as potent acetylcholinesterase inhibitors: in vitro and in silico analysis through kinetics,chemoinformatics and computational approaches |
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| Authors: | Mahajan Prasad G. Dige Nilam C. Vanjare Balasaheb D. Raza Hussain Hassan Mubashir Seo Sung-Yum Kim Chong- Hyeak Lee Ki Hwan |
| Affiliation: | 1.Department of Chemistry, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea ;2.Department of Biological Sciences, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea ;3.Institute of Molecular Biology and Biotechnology, The University of Lahore, Defence Road, Lahore, 54590, Pakistan ;4.Center for Chemical Analysis, Korea Research Institute of Chemical Technology, Yuseong, Daejeon, 34114, Republic of Korea ; |
| Abstract: | Molecular Diversity - We have designed and synthesized a novel acidic ionic liquid and explored its catalytic efficiency for the synthesis of 1,2,4-triazolidine-3-thione derivatives. A simple... |
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