Combinatorial libraries of bis-heterocyclic compounds with skeletal diversity |
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| Authors: | Soural Miroslav Bouillon Isabelle Krchnák Viktor |
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| Institution: | Department of Chemistry and Biochemistry, 251 Nieuwland Science Center, University of Notre Dame, Notre Dame, Indiana 46556, USA. |
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| Abstract: | Combinatorial solid-phase synthesis of bis-heterocyclic compounds, characterized by the presence of two heterocyclic cores connected by a spacer of variable length/structure, provided structurally heterogeneous libraries with skeletal diversity. Both heterocyclic rings were assembled on resin in a combinatorial fashion. |
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