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Biologisch aktive 3,3-Dimethylbicyclo[2.2.2]octane: Synthesen in der Isocamphanreihe, 35. Mitt. |
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| Authors: | Helmut Spreitzer Edith Rodinger Andrea Pichler Gerhard Buchbauer |
| Institution: | (1) Institut für Pharmazeutische Chemie, Universität Wien, A-1090 Wien, Österreich |
| Abstract: | Summary The bicyclo2.2.1]- and 2.2.2]-systems are part of numerous biological active substances. Continuing our syntheses in the isocamphane series the homologous isocamphanes of mecamylamine (1 a) and of the fungicidal bicyclic compound2 were synthesized. Furthermore the syntheses ofE-homoisosantalene (15) andE,E-homoisosantalol (16) are described. |
| Keywords: | 3 3-Dimethylbicyclo[2 2 2]octanes Biological activities Homomecamylamine Homocamphene Homocamphenilone E E-Homoisosantalole Woody odour Santalol analogues |
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