Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives |
| |
Authors: | Lim Sung-Gon Lee Jun Hee Moon Choong Woon Hong Jun-Bae Jun Chul-Ho |
| |
Institution: | Department of Chemistry, Yonsei Univeristy, Seoul 120-749, Korea. |
| |
Abstract: | reaction: see text] Novel synthetic methods of both ortho-alkenylated aromatic ketones and isoquinoline derivatives have been developed through the Rh(I)-catalyzed direct ortho-alkenylation of common aromatic ketimines with alkynes. Furthermore, a highly efficient one-pot synthesis of isoquinoline derivatives was achieved by simply mixing aromatic ketone, benzylamine, and alkyne under a Rh(I) catalyst. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|