两个非离子表面活性剂复配体系的NMR研究

通过核磁共振（NMR）技术对NP-10/Tween40和NP-10/C₁₀E₆两个复配体系在不同比例下混合胶束的排列方式、相互作用点及其不同分子间与相同分子间的作用变化进行了研究和比较.二维NOESY实验结果证明了：（1）这两种复配体系的相互作用是随混合比例的不同而变化的；（2）两个复配体系的不同分子间相互作用点有相同之处，但NP-10/Tween40分子间相互作用大于NP-10/C₁₀E₆.横向弛豫时间（T₂）表明，当NP-10/Tween40和NP-10/C₁₀E₆体系的混合比分别为1：2和1：4后，其不同分子间的相互作用开始减小，相同分子间作用开始起主导作用，暗示了复配体系中的理想混合配比和协同效应的变化.横向弛豫时间与纵向弛豫时间之比（T_R=T₂/T₁）反映了与NP-10/C₁₀E₆相比，NP-10/Tween40混合胶束分子链的运动受限更加严重.空间距离计算结果也佐证了NP-10/Tween40和NP-10/C₁₀E₆复配体系的较为理想的配比分别为1：2和1：4；NP-10/Tween40不同分子间距离小于NP-10/C₁₀E₆.

An NMR Study on Two Mixed Micelles Formed by Nonionic Surfactants

NMR techniques were used to study the relative arrangement and interaction sites in mixed micelles formed in NP-10/Tween40 and NP-10/C10E6 aqueous solutions.The results of two-dimensional NOESY experiments and relaxation time measurements showed that the interaction site of these two pairs of mixed surfactants were similar,but the intermolecular interaction between NP-10 and Tween40 was stronger than that between NP-10 and C10E6.T2 measurements demonstrated that inter-heteromolecular interactions decreased when the molar concentrations of Tween40 and C10E6 were larger than 2 and 4 folds of that of NP-10,respectively.Under such circumstances,the inter-homomolecular interactions began to play a key role,indicative of the ideal mixture molar ratio and the change of synergistic effect in the complex systems.T2/T1 ratio measurements indicated that molecular chain movement in the NP-10/Tween40 mixture was more limited than that in the NP-10/C10E6 mixture.The above conclusions were verified by spatial distance measurements.