Fabrication of size-controlled three-dimensional structures consisting of electrohydrodynamically produced polycaprolactone micro/nanofibers |
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Authors: | Soongee Hong and GeunHyung Kim |
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Institution: | (1) Department of Orthopaedics and Trauma Surgery, University Campus Bio-Medico of Rome, Via ?lvaro del Portillo, 200, 00128 Rome, Italy;(2) CIR - Tissue Engineering Laboratory, University Campus Bio-Medico of Rome, Via ?lvaro del Portillo, 21, 00128 Rome, Italy |
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Abstract: | In this paper, we report a facile method of fabricating size-controlled three-dimensional (3D) polycaprolactone (PCL) micro/nanofiber
structure using a modified electrospinning supplemented with a specially designed solvent bath in which the flow rate of the
solvent (EtOH) was controlled. By varying the flow rate of the EtOH into the grounded bath and the electrospinning parameters
including a distance between the nozzle and target, the height, diameter, porosity, and micro/nanofiber size of the 3D structures
were controlled. To show stable micro/nanofibrous structures under the fabricating conditions, we characterized a process
diagram for various flow rates of EtOH and weight percents of PCL. We believe that this modified electrospinning process may
be a new means of fabricating micro/nanofibrous 3D structures. |
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