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Conformational control of integrin-subtype selectivity in isoDGR peptide motifs: a biological switch
Authors:Frank Andreas O  Otto Elke  Mas-Moruno Carlos  Schiller Herbert B  Marinelli Luciana  Cosconati Sandro  Bochen Alexander  Vossmeyer Dörte  Zahn Grit  Stragies Roland  Novellino Ettore  Kessler Horst
Affiliation:1. Institute for Advanced Study, Technische Universit?t München, Department Chemie, Lichtenbergstrasse 4, 85747 Garching (Germany), Fax: (+49)?892‐891‐3210;2. Department of Molecular Medicine, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried (Germany);3. Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli “Federico II”, Via D. Montesano, 49‐80131 Napoli (Italy);4. Jerini AG, Invalidenstrassee 130, 10115 Berlin (Germany)
Abstract:
Keywords:cyclic pentapeptides  integrin ligands  isoDGR sequence  NMR spectroscopy  peptides
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