Glycosylated foldamers to probe the carbohydrate-carbohydrate interaction |
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| Authors: | Simpson Graham L Gordon Andrew H Lindsay David M Promsawan Netnepa Crump Matthew P Mulholland Keith Hayter Barry R Gallagher Timothy |
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| Institution: | School of Chemistry, University of Bristol, Bristol, BS8 1TS, UK. |
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| Abstract: | The synthesis of a triglycosylated helical foldamer based on a combination of cyclopentyl- and pyrrolidinyl-based amino acids is described. This structure is stable in water, maintaining as it does a series of carbohydrate units in proximity to one another, and represents the basis of a new approach to the study of carbohydrate-carbohydrate interactions. |
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