| 阿齐霉素的伏安行为研究 |
| |
| 引用本文： | 张国荣,王晓蕾,刘志先,庄庆媛. 阿齐霉素的伏安行为研究[J]. 分析化学, 2000, 28(1): 22-25 |
| |
| 作者姓名： | 张国荣 王晓蕾 刘志先 庄庆媛 |
| |
| 作者单位： | [1]山东师范大学化学系分析测试中心 [2]吉林市第二人民医院 |
| |
| 摘 要： | 在１．２ｍｏｌ／Ｌ ＮａＯＨ溶液中，阿齐霉素（ａｚｉｔｒｏｍｙｃｉｎ，简称ＡＺＭＣ）有一灵敏的还原伏安峰。当搅拌富集时间为１０s，扫速为５００ｍＶ／ｓ时其吸附伏 安溶出峰电位фp＝－１。３４Ｖ（ｖｓ．Ａｇ／ＡｇＣ１）。用线性扫描，计时库仑法，循环伏安及脉冲极谱等多种手段研究了该体系的伏安行为 和电极反应机理。实验表明该体系属于一有吸附性的不可逆过程，测得电极反应的电子转移数n＝２，体系的an＝１．１４
|
| 关 键 词： | 阿齐霉素 伏安行为 微分脉冲溶出法 示波极谱法 |
Voltammetric Behavior of Azitromycin |
| |
| Zhang Guorong, Wang xiaolei, Liu Zhixian. Voltammetric Behavior of Azitromycin[J]. Chinese Journal of Analytical Chemistry, 2000, 28(1): 22-25 |
| |
| Authors: | Zhang Guorong Wang xiaolei Liu Zhixian |
| |
| Abstract: | In 1. 2 mol/L NaOH solution, a sensitive reductive peak of Azitromycin (AZMC) was observed at - 1. 34V (vs. Ag/AgCl). The voltammetric behavior has been studied by means of cyclic voltammetry, differential pulse polarography and chronocoulometry etc. The number of electron transfer has been determined to be 2. The wave confirmed to be irrversible and adsorptive has been applied to the determination of AZMC. The linear relationship between peak height and the concentration of AZMC held in the range of0. 005 ~ 10mg/L and 0 .05 ~ 20 mg/L by adsoptive differential stripping voltamtry and single sweep polarography, respectively. This method has been used successfully to determine Azitromycin in tablet and capsule. |
| |
| Keywords: | Azitromycin voltammetric behavior adsorptive differential pulse stripping voltmmetry oscillopolarography |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
