| 用于生物微反应器pH在线监测光纤传感器研究 |
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| 引用本文： | 王军波,吴旻宪,崔铮,崔占峰.用于生物微反应器pH在线监测光纤传感器研究[J].微纳电子技术,2007(Z1). |
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| 作者姓名： | 王军波 吴旻宪 崔铮 崔占峰 |
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| 作者单位： | 中国科学院电子学研究所传感技术国家重点实验室，英国卢瑟福国家实验室，英国卢瑟福国家实验室，英国牛津大学工程系 北京100080，英国卢瑟福国家实验室，牛津OX110QX，牛津OX110QX，牛津OX110QX，牛津OX13PJ |
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| 摘 要： | 以生物微反应器中培养液pH在线监测为目标,研制出一种基于光度吸收原理的阵列光纤传感器。利用MEMS加工工艺,制备出传感器的阵列吸光池芯片,采用光学软件对吸光池进行优化设计,提高了传感器光传输效率,并通过CFD软件进行流体模拟,优化吸光池结构,降低了溶液死体积,缩短传感器响应时间。实验结果表明,所研究的传感器阵列检测灵敏度为0.83V/pH,响应速度快,可用于多个生物微反应器的pH在线监测。
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| 关 键 词： | 光纤传感器 生物微反应器 微机电系统 在线监测 阵列 |
Optical Fibre Sensor for On-Line Monitoring of pH in Microbioreactor |
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| WANG Jun-bo,WU Min-xian,CUI Zheng,CUI Zhan-feng.Optical Fibre Sensor for On-Line Monitoring of pH in Microbioreactor[J].Micronanoelectronic Technology,2007(Z1). |
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| Authors: | WANG Jun-bo WU Min-xian CUI Zheng CUI Zhan-feng |
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| Institution: | WANG Jun-bo1,WU Min-xian2,CUI Zheng2,CUI Zhan-feng3 |
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| Abstract: | A novel optical fibre sensor array based on Lambert-Beer law was developed for online monitoring of pH in microbioreactor.It was fabricated through MEMS processing.Different thicknesses of detection pole were tested by optical simulation to acquire high light transmission efficiency.Two kinds of detection pole structures were analyzed by CFD simulation to minimize the dead zone and shorten response time of the sensor.Experiments show that the sensitivity of the optical fibre sensor array is 0.83 V/pH and it can be used for on-line monitoring of pH in multi-microbioreactor with shorter response time. |
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| Keywords: | optical fibre sensor micro-bioreactor MEMS on-line monitoring array |
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