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Aza-Michael Addition of Isatin and Phthalimide to Symmetrical Fumaric Esters in Ionic Liquid Media
Authors:IMANZADEH Gholam Hassan  MOLLAEI TAVANA Mahdieh  ZAMANLOO Mohammad Reza  MANSOORI Yagoub
Institution:1. Tel.: 0098‐451‐5514701;2. Fax: 0098‐451‐5514702;3. Department of Chemistry, College of Science, University of Mohaghegh Ardabili 56199‐11367, Ardabil, Iran
Abstract:Highly efficient aza‐Michael additions of isatin and phthalimide to symmetrical fumaric esters in ionic liquid media to produce the corresponding Michael adducts in excellent yields are described which were performed at 100 °C for 1–5 h. The results show that these aza‐Michael additions are not effective with fumaric esters containing sterically hindered alkoxy groups.
Keywords:aza‐Michael addition  isatin  phthalimide  fumaric ester  ionic liquid medium
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