Syntheses of 4-deoxy-d-fructose and enzymatic affinity study |
| |
| Affiliation: | 1. Université de Toulouse, INSA, UPS, INP, LISBP, 135 Avenue de Rangueil, F-31077 Toulouse, France;2. INRA, UMR792 Ingénierie des Systèmes Biologiques et des Procédés, F-31400 Toulouse, France;3. CNRS, UMR5504, F-31400 Toulouse, France;4. INRA, UMR1163 Biotechnologie des Champignons Filamenteux, Aix-Marseille Université, Polytech Marseille, 163 Avenue de Luminy, CP 925, F-13288 Marseille, France;5. Aix-Marseille Université, UMR1163 Biotechnologie des Champignons Filamenteux, Faculté des Sciences de Luminy-Polytech, CP 925, F-13288 Marseille Cedex 9, France;1. Oncology Business Unit, Nerviano Medical Sciences, Viale Pasteur 10, 20014 Nerviano (MI), Italy;2. Dipartimento di Scienze Farmaceutiche “Pietro Pratesi”, Università degli Studi di Milano, Via Mangiagalli 25, 20133 Milan, Italy |
| |
| Abstract: | Enantiomerically pure 4-deoxy-d-fructose has been prepared and characterised in a protected form, acidic hydrolysis of which led to an aqueous solution of 4-deoxy-d-fructose. Activities of this compound with enzymes of the glycolysis pathway involved in glucose metabolism make possible access to 4-deoxy-d-fructose-6-phosphate, 4-deoxy-d-glucose-6-phosphate and 4-deoxy-d-gluconate-6-phosphate. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
