Enantioselectivity of a recombinant epoxide hydrolase from Agrobacterium radiobacter |
| |
| Affiliation: | 1. Shandong Key Laboratory of TCM Quality Control Technology, Shandong Analysis and Test Center, Jinan 250014, PR China;2. College of Chinese Mareria Medica, Beijing University of Chinese Medicine, Beijing 100102, PR China |
| |
| Abstract: | The recombinant epoxide hydrolase from Agrobacterium radiobacter AD1 was used to obtain enantiomerically pure epoxides by means of a kinetic resolution. Epoxides such as styrene oxide and various derivatives thereof and phenyl glycidyl ether were obtained in high enantiomeric excess and in reasonable yield. The enantioselectivity (E-value) of the resolution was calculated from progress curves for styrene oxide (E=16.2) and para-chlorostyrene oxide (E=32.2). |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
