A rationally designed macrocyclic cavitand that kills bacteria with high efficacy and good selectivity |
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Authors: | Choi Jinny Kim Jeeyeon Kim Kimoon Yang Sung-Tae Kim Jae-Il Jon Sangyong |
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Institution: | Department of Life Science, Gwangju Institute of Science and Technology, Gwangju 500-712, Korea. |
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Abstract: | An amphiphilic macrocyclic cavitand that shows good antibacterial activity, comparable to that of peptide-based antibiotics was developed by rational design and its antibacterial selectivity over mammalian cells was examined. |
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