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A rationally designed macrocyclic cavitand that kills bacteria with high efficacy and good selectivity
Authors:Choi Jinny  Kim Jeeyeon  Kim Kimoon  Yang Sung-Tae  Kim Jae-Il  Jon Sangyong
Institution:Department of Life Science, Gwangju Institute of Science and Technology, Gwangju 500-712, Korea.
Abstract:An amphiphilic macrocyclic cavitand that shows good antibacterial activity, comparable to that of peptide-based antibiotics was developed by rational design and its antibacterial selectivity over mammalian cells was examined.
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