High-resolution,three-dimensional diffusion-weighted breast imaging using DESS |
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| Affiliation: | 1. Radiology, Stanford University, Stanford, CA 94305;2. Electrical Engineering, Stanford University, Stanford, CA 94305;1. Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA;2. Instituto de Radiologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil;3. Department of Radiology, Charité Universitätsmedizin Berlin, Berlin, Germany;4. Department of Imaging, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA;5. Department of Radiology, Sahlgrenska University Hospital, Gothenburg University, Gothenburg, Sweden;6. Department of Radiology, Children’s Hospital Boston, Harvard Medical School, Boston, MA;1. Department of Radiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China;2. Global Applied Science Laboratory, GE Healthcare, Shanghai 201203, China |
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| Abstract: | PurposeTo evaluate the use of the double-echo steady-state (DESS) sequence for acquiring high-resolution breast images with diffusion and T2 weighting.Materials and MethodsPhantom scans were used to verify the T2 and diffusion weighting of the DESS sequence. Image distortion was evaluated in volunteers by comparing DESS images and conventional diffusion-weighted images (DWI) to spoiled gradient-echo images. The DESS sequence was added to a standard clinical protocol, and the resulting patient images were used to evaluate overall image quality and image contrast in lesions.ResultsThe diffusion weighting of the DESS sequence can be easily modulated by changing the spoiler gradient area and flip angle. Radiologists rated DESS images as having higher resolution and less distortion than conventional DWI. Lesion-to-tissue contrast ratios are strongly correlated between DWI and DESS images (R = 0.83) and between T2-weighted fast spin-echo and DESS images (R = 0.80).ConclusionThe DESS sequence is able to acquire high-resolution 3D diffusion- and T2-weighted images in short scan times, with image quality that facilitates morphological assessment of lesions. |
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