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Synthesis and properties of new biotin compounds containing hexyltriethylene glycol chain
Authors:Algirdas Matijoška  Tatjana Charkova  Zenonas Kuodis  Vladislava Voiciuk  Olegas Eicher-Lorka
Institution:(1) School of Chemical and Environmental Engineering, Beijing Technology and Business University, No. 11 Fucheng Road, 100048 Haidian District, Beijing, People’s Republic of China
Abstract:The synthesis of a new halogenide containing hexyltriethylene glycol chain functionalized with biotin is reported. The general possibility of this linker to use as the building block for biotinylated compounds syntheses is demonstrated. Two biotinylated esters with different properties for useful surface modification and as fluorescence probes for proteins marking were synthesized. The properties of mentioned compounds were investigated by using surface plazmon resonance ellypsometry and fluorescence spectroscopy.
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