A New Glycine Derivative and a New Indole Alkaloid from the Fermentation Broth of the Plant Endophytic Fungus Pestalotiopsis podocarpi Isolated from the Chinese Podocarpaceae Plant Podocarpus macrophyllus |
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| Authors: | Du‐Qiang Luo Yu‐Peng Chen Jun Zhang Bao‐Zhong Shi Zi‐Qi Yang Chuan Chen |
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| Institution: | 1. Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding 071002, P.?R. China;2. College of Life Science, Hebei University, Baoding 071002, P.?R. China |
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| Abstract: | A new glycine derivative, podocarpiamide ( 1 ), a new indole alkaloid, 1‐methoxy‐1H‐indol‐3‐ethanol ( 2 ), together with two known compounds, 1‐methoxy‐1H‐indole‐3‐acetic acid ( 3 ) and methyl 1‐methoxy‐1H‐indole‐3‐acetate ( 4 ), were isolated from the fermentation broth of the plant endophytic fungus Pestalotiopsis podocarpi. Their structures were elucidated by extensive spectroscopic analysis including 1D‐ and 2D‐NMR (HSQC, HMBC, and COSY) and MS experiments. Compound 1 has an interesting unusual carbamic acid structure. |
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| Keywords: | Pestalotiopsis podocarpi Podocarpiamide Glycine derivatives 1H‐Indol‐3‐ethanol 1‐methoxy‐ |
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