Two New Chemical Constituents of Veratrum dahuricum (Turcz.) Loes. f. |
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| Authors: | Yue Cong Jing‐Gong Guo Jing Liu |
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| Institution: | 1. Institute of Pharmacy, Pharmaceutical College, Henan University, Jinming Road, Kaifeng 475004, P.?R. China (phone/fax: +86‐378‐3880680);2. The Key Laboratory of Plant Stress Biology, Henan University, Jinming Road, Kaifeng 475004, P.?R. China |
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| Abstract: | Two new chemical constituents, one new steroid, neoveratrenone ( 1 ), and one new glycerol ester, 1‐11‐(ferulyloxy)undecanoyl)]glycerol ( 2 ), were isolated and characterized from the roots and rhizomes of Veratrum dahuricum (Turcz .) Loes . f., together with five known compounds, i.e., hexacosanoic acid 2,3‐dihydroxypropyl ester ( 3 ), syringaresinol ( 4 ), prosapogenin A of dioscin ( 5 ), verapatulin ( 6 ), and oxyresveratrol ( 7 ). Their structures were established by extensive analysis of spectroscopic data as well as by comparison with literature reports. The compounds were evaluated for cytotoxic activity against three tumor cell lines of HepG‐2, HeLa, and K562/S. |
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| Keywords: | Veratrum dahuricum Neoveratrenone Glycerol 1‐[11‐(ferulyloxy)undecanoyl)]‐ Cytotoxic activity |
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