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Gly‐Gly‐His Immobilized On Monolayer Modified Back‐Side Contact Miniaturized Sensors for Complexation of Copper Ions |
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| Authors: | Urszula E Wawrzyniak Patrycja Ciosek Micha? Zaborowski Guozhen Liu J Justin Gooding |
| Institution: | 1. Department of Microbioanalytics, Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, 00–664 Warsaw, Poland;2. School of Chemistry and Australian Centre for NanoMedicine, The University of New South Wales, Sydney, NSW2052, Australia;3. Institute of Electron Technology, Al. Lotników 32/46, 02‐668 Warsaw, Poland;4. Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P.?R. China |
| Abstract: | Miniaturized planar back‐side contact transducers (BSC) with chemically modified gold surface have been utilized as electrochemical sensors. The electrodes have been functionalized by sequential immobilization of aryl diazonium salts or alkanethiols and short peptide Gly‐Gly‐His. The applicability of gold substrates modified with aryl diazonium salts in voltammetric detection of copper(II) ions in aqueous solutions has been studied. The combination of two fundamental elements of the solid‐state electrode, i.e. back‐side contact (BSC) gold sensor and self‐assembled monolayers, allowed one to obtain reliable miniaturized copper(II) ion sensors. It can have important future applications in environmental sensing or in implantable biodevices. |
| Keywords: | Back‐side contact gold electrodes Miniaturized biosensors Gly‐Gly‐His Copper(II) ions Aryl diazonium salts Self‐assembled monolayers |