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Cucurbitane‐Type Triterpenoids from Momordica charantia
Authors:Bao‐Hui Cheng  Jian‐Chao Chen  Jie‐Qing Liu  Lin Zhou  Ming‐Hua Qiu
Institution:State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P.?R. China, (phone/fax: +86‐0871‐5223255)
Abstract:The six new cucurbitane‐type triterpenoids 1 – 6 , along with the ten known triterpenoids 7 – 16 , were isolated from the vines and leaves of Momordica charantia. The structures of the new compounds were elucidated as (3β,7β,15β,23E)‐3,7,15,25‐tetrahydroxycucurbita‐5,23‐dien‐19‐al ( 1 ), (3β,7β)‐3,7,22,23‐tetrahydroxycucurbita‐5,24‐dien‐19‐al ( 2 ), (3β,7β)‐3,7,23,24‐tetrahydroxycucurbita‐5,25‐dien‐19‐al ( 3 ), (3β,7β,23S)‐3,7,23‐trihydroxycucurbita‐5,24‐dien‐19‐al 7‐β‐D ‐glucopyranoside ( 4 ), (3β,7β,23E)‐cucurbita‐5,23‐diene‐3,7,19,25‐tetrol 7‐β‐D ‐glucopyranoside ( 5 ), and (3β,7β,23E)‐3,7‐dihydroxy‐25‐methoxy‐cucurbita‐5,23‐dien‐19‐al 3‐β‐D ‐allopyranoside ( 6 ), by extensive analyses of their spectral data, as well as by chemical methods.
Keywords:Momordica charantia  Cucurbitanes  Triterpenes
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