An Environmental Friendly Approach for the Synthesis of Spiro[indoline‐3′,2‐quinazoline]2′,4(3H)‐dione Using 1‐Methylimidazolium Hydrogen Sulfate,as Reusable Catalyst |
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| Authors: | Hassan Kefayati Masoumeh Vazifeh Reyhaneh Kazemi‐Rad |
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| Institution: | 1. Department of Chemistry, Science and Research Branch, Islamic Azad University, Guilan, Iran;2. Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran;3. Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran |
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| Abstract: | A facile and environmentally benign procedure for the synthesis of 3‐aryl‐1H‐spiroindoline‐3′,2‐quin‐azoline]2′,4(3H)‐dione from isatoic anhydride, aromatic amines and isatin derivatives in Brønsted acidic ionic liquid, 1‐methylimidazolium hydrogen sulfate, was reported. The ability to reuse the ionic liquid, the high yield, short reaction time and ease of purification are the important features of this process. |
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| Keywords: | Isatin Isatoic anhydrid Spiro[indoline‐quinazoline]one 1‐Methylimidazolium hydrogen sulfate Multi component reaction |
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