Deposition Strategies for Osmium/Enzyme Films on Gold Electrode Based Sensing Arrays |
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| Authors: | Jennifer R McKenzie Chengxiao Zhang Chen‐Zhong Li |
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| Institution: | 1. Nanobioengineering/Bioelectronics Lab, Department of Biomedical Engineering, Florida International University, Miami, FL, USA;2. Department of Chemistry, Vanderbilt University, Nashville, TN, USA;3. Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Material Science, Shaanxi Normal University, Xi'an 710062, P.?R. China |
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| Abstract: | Multi‐analyte real‐time interrogation of cellular activity allows for the potential discovery of novel insights into disease. In this report, the addition of electrochemical biosensors to a previously developed platform utilizing Au microfabricated electrodes was explored. Glucose oxidase was immobilized at the electrode surface with an osmium redox polymer, using hand‐casting and electrodeposition techniques, allowing for the first comparison of deposition techniques at a Au microfabricated array. This preliminary work is the first step toward the goal of creating a multi‐analyte array for cellular analysis. |
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| Keywords: | Osmium polymer Electrodeposition Biosensor Gold microfabricated electrode Enzyme |
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