| 2D NMR研究呋喃糖Grignard加成产物的绝对构型 |
| |
| 引用本文： | 张铭龙,崔育新,刘雪辉,李敬光,马灵台,张礼和. 2D NMR研究呋喃糖Grignard加成产物的绝对构型[J]. 波谱学杂志, 1999, 16(3): 219-224 |
| |
| 作者姓名： | 张铭龙 崔育新 刘雪辉 李敬光 马灵台 张礼和 |
| |
| 作者单位： | 北京医科大学药学院 天然药物及仿生药物国家重点实验室, 北京 100083 |
| |
| 摘 要： | 通过对相应呋喃糖进行Grignard亲和加成合成了苯基及苄基取代呋喃糖.所得主要产物的结构和绝对构型通过二维核磁共振进行了研究.其结果通过计算机分子模拟优化,并进行了比较和确认.
|
| 关 键 词： | Grignard亲和加成 绝对构型 二维核磁共振 计算机分子模拟 |
| 收稿时间： | 1999-01-25 |
STUDY ON THE SYNTHESIS AND ABSOLUTE CONFIGURATIONS OF GRIGNARD ADDITION PRODUCTS OF FURANOSES BY 2D NMR |
| |
| Zhang Minglong,Cui Yuxin,Liu Xuehui,Li Jingguang,Ma Lingtai,Zhang Lihe. STUDY ON THE SYNTHESIS AND ABSOLUTE CONFIGURATIONS OF GRIGNARD ADDITION PRODUCTS OF FURANOSES BY 2D NMR[J]. Chinese Journal of Magnetic Resonance, 1999, 16(3): 219-224 |
| |
| Authors: | Zhang Minglong Cui Yuxin Liu Xuehui Li Jingguang Ma Lingtai Zhang Lihe |
| |
| Affiliation: | The National Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083 |
| |
| Abstract: | Phenyl and benzyl furanoses have been prepared stereoselectively by Grignard nucleophilic addition to their correspondent furanoses. Their structures and absolute configurations were studied and described by measuring the two dimensional NMR spectroscopy. The results have been compared and confirmed by computational optimizing model data. |
| |
| Keywords: | Grignard nucleophilic addition Absolute configuration 2D NMR spectroscopy Computational optimizing |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《波谱学杂志》浏览原始摘要信息 |
|
点击此处可从《波谱学杂志》下载全文 |
