Detection of activated, TIMP-free MMPs |
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| Authors: | Zucker Stanley Cao Jian |
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| Institution: | Department of Research and Medicine, VA Medical Center, Northport, New York 11768, USA. |
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| Abstract: | MMP inhibitor-tethered resins provide a method for detection of activated MMPs in tissues. These measurements will help to elucidate in situ mechanisms of MMP activation, further our understanding of the tumor microenvironment, and facilitate development of MMP-inhibitor therapy. |
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