New 3,4-seco-ent-kaurene dimers from Croton micans |
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Authors: | Mateu Elsa Chavez Katiuska Riina Ricarda Compagnone Reinaldo S Delle Monache Franco Suárez Alírica I |
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Affiliation: | Facultad de Farmacia, Universidad Central de Venezuela, Caracas, Venezuela. |
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Abstract: | From the stems of Croton micans Sw., five new 3,4-seco-ent-kaurene dimers: micansinoic acid (1), isomicansinoic acid (2), and the dimethyl (3), monomethyl (4) and monoethyl ester (5) of micansinoic acid were isolated. The structures of the new compounds were elucidated by spectroscopic data interpretation, mainly 1D and 2D NMR experiments and MS. These compounds are the first 3,4-seco-ent-kaurene dimers from a Croton species. |
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