Dirhodium(II) Carboxylate Catalyzed Formation of 1,2,3‐Trisubstituted Indoles from Styryl Azides |
| |
| Authors: | Crystalann Jones Quyen Nguyen Prof?Dr Tom G Driver |
| |
| Institution: | Department of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago (USA) http://www.chem.uic.edu/driver |
| |
| Abstract: | Dirhodium(II)‐carboxylate complexes were discovered to promote the selective migration of acyl groups in trisubstituted styryl azides to form 1,2,3‐trisubstituted indoles. The styryl azides are readily available in three steps from cyclobutanone and 2‐iodoaniline. |
| |
| Keywords: | azides electrocyclic reactions indole rhodium synthetic methods |
|
|
