Controlled Trifluoromethylation Reactions of Alkynes through Visible‐Light Photoredox Catalysis |
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| Authors: | Naeem Iqbal Jaehun Jung Sehyun Park Prof Dr Eun Jin Cho |
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| Institution: | 1. Department of Chemistry and Applied Chemistry, Hanyang University, 55 Hanyangdaehak‐ro, Sangnok‐gu Ansan, Kyeonggi‐do 426‐791 (Republic of Korea);2. Department of Bionanotechnology, Hanyang University (Republic of Korea) |
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| Abstract: | The control of a reaction that can form multiple products is a highly attractive and challenging concept in synthetic chemistry. A set of valuable CF3‐containing molecules, namely trifluoromethylated alkenyl iodides, alkenes, and alkynes, were selectively generated from alkynes and CF3I by environmentally benign and efficient visible‐light photoredox catalysis. Subtle differences in the combination of catalyst, base, and solvent enabled the control of reactivity and selectivity for the reaction between an alkyne and CF3I. |
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| Keywords: | iridium radical reactions ruthenium trifluoromethylation visible light |
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