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不同电解质溶液对脂质体Zeta电势的影响
引用本文:童华,姚松年.不同电解质溶液对脂质体Zeta电势的影响[J].物理化学学报,1998,14(11):1043-1047.
作者姓名:童华  姚松年
作者单位:Department of Analysis and Measurement in Wuhan University,Wuhan 430072
基金项目:国家自然科学基金,山东大学胶体与界面国家重点实验室资助
摘    要:卵磷脂(PC)在水溶液中形成类似细胞的脂双层闭合体——脂质体.以它为模型研究水溶液中无机离子与磷脂分子极性端基的作用,对解释生理环境中脂质体的物理化学行为有重要的意义.Tatulian1]用电泳法给出了一系列一价阴离子与PC膜表面亲合强弱的排序,Eisenberg等2]测定了一

关 键 词:显微电泳  Zeta电势  卵磷脂  胆固醇  
收稿时间:1997-12-03
修稿时间:1998-03-19

Effect of Different Types of Electrolyte on Surface Potential of Liposome of PC and PC-Cholesterol
Tong Hua, Yao Songnian.Effect of Different Types of Electrolyte on Surface Potential of Liposome of PC and PC-Cholesterol[J].Acta Physico-Chimica Sinica,1998,14(11):1043-1047.
Authors:Tong Hua  Yao Songnian
Institution:Department of Analysis and Measurement in Wuhan University,Wuhan 430072
Abstract:Zeta potential of PC and PC-Cholesterol liposome was measured by microelectrophoretic mobility in the presence of different types of electrolyte. A combination of GouyChapman-Stern theory and Poisson-Boltzmann equation was used to describe the regularity of the dependence of Zeta potential on several cations and anions with different valencies. Interaction mechanism of cation, anion and cholesterol with PC polar head group was discussed. The electrostatic force is dominated in influencing the surface potential of liposome.
Keywords:Microelectrophoretic  Zeta potential  Phosphatidyl choline (PC)  Cholesterol  
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