Copper(II)-catalyzed ortho-functionalization of 2-arylpyridines with acyl chlorides |
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Authors: | Wang Wenhui Pan Changduo Chen Fan Cheng Jiang |
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Affiliation: | College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325000, People's Republic of China. |
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Abstract: | Copper-catalyzed ortho-benzoxylation of 2-arylpyridine sp(2) C-H bonds with acyl chloride is described. Notably, switching the base from t-BuOK to Li(2)CO(3) causes chlorination of the C-H bond to take place. |
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