High-relaxivity MRI contrast agents prepared from miniemulsion polymerization using gadolinium(III)-based metallosurfactants |
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| Authors: | Gong Pei Chen Zhengyan Chen Yingying Wang Wei Wang Xiaosong Hu Aiguo |
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| Affiliation: | Key Lab for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Rd, Shanghai, 200237, China. |
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| Abstract: | Miniemulsion polymerization with amphiphilic gadolinium(III) complexes as metallosurfactants was explored as a new technique for the synthesis of high relaxivity MRI contrast agents. Well-defined metallo-colloids with up to 240% enhancement in relaxivity over their small molecular counterparts were obtained. |
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