Application of tandem Ugi multi-component reaction/ring closing metathesis to the synthesis of a conformationally restricted cyclic pentapeptide |
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Authors: | Dietrich Silvia Anthoine Banfi Luca Basso Andrea Damonte Gianluca Guanti Giuseppe Riva Renata |
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Institution: | Department of Chemistry and Industrial Chemistry, via Dodecaneso 31, 16146, Genova, Italy. |
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Abstract: | A conformationally restricted cyclic pentapeptide, containing an unsaturated 9-membered lactam as a semi-rigid scaffold, was prepared in a very convergent manner, through tandem Ugi reaction/ring closing metathesis. |
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