New extraction procedure to improve the determination of quinolones in poultry muscle by liquid chromatography with ultraviolet and mass spectrometric detection |
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Authors: | Bailac S Barrón D Barbosa J |
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Affiliation: | aDepartment of Analytical Chemistry, University of Barcelona, Avda. Diagonal 647, E-08028 Barcelona, Spain |
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Abstract: | The present article aims to develop a new extraction procedure to improve the determination of quinolones in chicken muscle. This new determination method was validated using liquid chromatography–ultraviolet detection (LC–UV) and liquid chromatography–mass spectrometry detection (LC–MS), which has special bearing on stability studies. The results obtained by using the method were compared with the results obtained with a previous methodology. The new extraction procedure presents a sensitivity low enough to determine concentration of these drugs below the permissible maximum residue limits (MRL) in chicken muscle and is less time consuming than the previous methodology. |
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Keywords: | Liquid chromatography Mass spectrometry Ultraviolet detection Chicken tissues and quinolones |
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