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Nanomaterials in Cerebrovascular Disease Diagnose and Treatment
Authors:Yin Luo  Yanting Wang  Jie Fu
Institution:1. School of Environmental Science and Engineering, Huazhong University of Science and Technology, Wuhan, 430074 China

Department of Biomedical Engineering, School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074 China;2. School of Pharmacy, Second Military Medical University, Shanghai, 200433 China;3. School of Environmental Science and Engineering, Huazhong University of Science and Technology, Wuhan, 430074 China

Abstract:Cerebrovascular diseases (CVDs) are among the most serious diseases with high mortality and disability rates. The prevalent diagnosis and treatment methods of CVDs include imaging and interventional therapy. With the development of nanotechnology, large numbers of nanomaterials have been applied to the diagnosis and treatment of CVDs, mainly including carbon nanotubes, quantum dots, fullerenes, and dendrimers. In this review, the applications of nanomaterials in the field of diagnosis and treatment of CVDs, mainly including drug target delivery, imaging, therapy, endovascular treatment, and angiogenesis, are summarized. The applications of nanomaterials in the field of CVD are almost in the laboratory, and more effort is needed for clinical translation. The aim of this review is to provide useful information for future research and equipment development.
Keywords:cerebrovascular diseases  drug delivery  imaging  nanomaterials  therapies
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