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Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa lectin I (PA-IL) using a DNA-based carbohydrate microarray |
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| Authors: | Chevolot Yann Zhang Jing Meyer Albert Goudot Alice Rouanet Sonia Vidal Sébastien Pourceau Gwladys Cloarec Jean-Pierre Praly Jean-Pierre Souteyrand Eliane Vasseur Jean-Jacques Morvan François |
| Affiliation: | INL UMR5270 CNRS Ecole Centrale de Lyon, 36 avenue G. de Collongue, 69134 Ecully Cedex, France. yann.chevolot@ec-lyon.fr |
| Abstract: | The binding of seven multivalent glycoconjugates displaying linear or antenna-like structures and different electronic environments were evaluated towards PA-IL on a DNA-based carbohydrate microarray. The affinity can be modulated by the charge and the topology of the galactosylated derivatives. |
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