In vitro biological activities and fatty acid profiles of Pistacia terebinthus fruits and Pistacia khinjuk seeds |
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| Authors: | I¸?l Hac?bekiro?lu Pelin Köseo?lu Y?lmaz Nesrin Ha¸imi Ersin K?l?nç Veysel Tolan |
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| Institution: | 1. Department of Analytical Chemistry, Faculty of Pharmacy, Bezmialem Vakif University, 34093Istanbul, Turkey;2. Department of Analytical Chemistry, Faculty of Pharmacy, Istanbul University, 34116Istanbul, Turkey;3. Department of Nutrition and Dietetics, School of Health, Batman University, 72060Batman, Turkey;4. Department of Chemistry, Faculty of Art and Science, Dicle University, 21280Diyarbakir, Turkey;5. Department of Biology, Faculty of Art and Science, Dicle University, 21280Diyarbakir, Turkey |
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| Abstract: | This study reports in vitro anticholinesterase, antioxidant and antimicrobial effects of the n-hexane, dichloromethane, ethanol and ethanol–water extracts prepared from Pistacia terebinthus L. fruits and Pistacia khinjuk Stocks seeds as well as their total phenolic and flavonoid contents, and fatty acid compositions. Ethanol and ethanol–water extracts of both species exhibited higher anticholinesterase activity than galanthamine. Among ABTS, DPPH and CUPRAC assays, the highest antioxidant capacity of the extracts was found in the last one. P. terebinthus ethanol extract being rich in flavonoid content showed the best cupric reducing effect. All extracts possessed no antimicrobial activity. The main fatty acid in P. terebinthus fruits (52.52%) and P. khinjuk seeds (59.44%) was found to be oleic acid. Our results indicate that P. terebinthus fruits and P. khinjuk seeds could be a good source of anticholinesterase compounds, and could be phytochemically investigated. |
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| Keywords: | Anacardiaceae Pistacia terebinthus Pistacia khinjuk anticholinesterase antioxidant fatty acid |
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