Antioxidant and antifungal activity of different extracts obtained from aerial parts of Inula crithmoides L. |
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Authors: | Anahi Bucchini Donata Ricci Federica Messina Maria Carla Marcotullio Massimo Curini |
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Affiliation: | 1. Dipartimento di Scienze della Terra, della Vita e dell'Ambiente – Università di Urbino “Carlo Bo”, Via Bramante 28, 61029 Urbino (PU), Italy;2. Dipartimento di Scienze Biomolecolari, Università di Urbino “Carlo Bo”, Via Bramante 28, 61029 Urbino (PU), Italy;3. Dipartimento di Scienze Farmaceutiche, Università di Perugia, Via del Liceo 1, 06123 Perugia (PG), Italy |
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Abstract: | The total phenolic content, antioxidant and antifungal activities of three Inula crithmoides extracts (n-hexane, methylene chloride and MeOH) were investigated. The methanolic extract showed the highest total phenolic content. In the DPPH assay, the methanolic and hexane extracts exhibited the highest DPPH-radical scavenging activity; in the 5-lipoxygenase assay, the hexane extract showed greater inhibitory effect with an IC50 similar to that of Trolox and ascorbic acid. The antifungal activity of the methanolic extract revealed a higher activity against Phytophtora cryptogea and Alternaria solani. |
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Keywords: | Inula crithmoides phenolics antioxidant activity antifungal activity |
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