A new aldehyde compound from the fruit of Pandanus tectorius Parkinson ex Du Roi |
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| Authors: | Dinh Tri Mai Tien Dung Le Tan Phat Nguyen Nhat Minh Phan Huu An Nguyen Thi Thanh Phuc Nguyen |
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| Affiliation: | 1. Bioactive Compounds Laboratory, Institute of Chemical Technology, Vietnam Academy of Science and Technology, 01 Mac Dinh Chi Street, District 1, Ho Chi Minh City, Vietnam;2. Faculty of Chemistry, University of Science, Vietnam National University, 227 Nguyen Van Cu Street, District 5, Ho Chi Minh City, Vietnam |
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| Abstract: | From the fruit of Pandanus tectorius Parkinson ex Du Roi, one new (1) and six known aldehyde compounds (2–7) were isolated by various chromatography methods. Based on their spectroscopic data, these compounds were identified as (Z)-4-hydroxy-3-(4-hydroxy-3-methylbut-2-en-1-yl) benzaldehyde (1), p-hydroxybenzaldehyde (2), syringaldehyde (3), (E)-ferulaldehyde (4), (E)-sinapinaldehyde (5), vanillin (6) and 5-hydroxymethylfurfual (7). The α-glucosidase inhibitory activity of all compounds was measured. The isolated compounds (1–6) showed better α-glucosidase inhibitory activity (IC50 values ranging from 36.5 to 192.4 μM) than the standard drug acarbose (IC50 = 214.5 μM). |
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| Keywords: | Pandanus tectorius new aldehyde α-glucosidase |
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