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Antimicrobial and antioxidant activities of a new benzamide from endophytic Streptomyces sp. YIM 67086
Authors:Xueqiong Yang  Tianfeng Peng  Yabin Yang  Wei Li  Jie Xiong  Lixing Zhao
Institution:1. Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, P.R. China;2. Yunnan Institute of Microbiology, Yunnan University, Kunming 650091, P.R. China
Abstract:A new benzamide (1) and four known compounds (25) were isolated from endophytic Streptomyces YIM67086, and their structures were determined as 2-amino-3,4-dihydroxy-5-methoxybenzamide (1), 4-hydroxy-3-methoxybenzoic acid (2), phenylacetic acid (3), N-acetyltyramine (4) and p-hydroxytruxinic acid (5). Compound 5 was first found in the microorganism. The antimicrobial activities of compounds 15 and antioxidant activity of compound 1 were investigated.
Keywords:Streptomyces sp  benzamide  antimicrobial activities  antioxidant activity
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