A new ellagic acid derivative from Polygonum runcinatum |
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Authors: | Zhi-Hong Zhou Min-Zhuo Liu Meng-Hua Wang Wei Qu Jian-Bo Sun |
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Institution: | Department of Natural Medicinal Chemistry, China Pharmaceutical University, #24 Tongjiaxiang, Nanjing 210009P.R. China |
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Abstract: | A new ellagic acid derivative, 3,3′-dimethylellagic acid-4′-O-(6″-galloyl)-β-d-glucoside, named runcinatside (5), together with four known compounds 3,3′-dimethylellagic acid (1), 3,3′,4′-trimethylellagic acid (2), 3,3′-dimethylellagic acid-4′-O-β-d-glucoside (3) and 3-methylellagic acid-4′-O-α-l-rhamno-pyranoside (4), was isolated from the roots of Polygonum runcinatum Buch.-Ham. ex D.Don Var. sinense Hemsl and the structures of these compounds were established by spectroscopic methods and comparison with previously reported data. All compounds showed antioxidant activities in vitro and compound 5 possessed the highest activity. |
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Keywords: | Polygonum runcinatum chemical constituents ellagic acid derivative antioxidant activity |
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