A new biflavonoid from Solanum dulcamara L. and investigation of anti-hyperglycaemic activity of its fruit extract |
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| Authors: | Temine Sabudak Oktay Kaya Elif Cukurova |
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| Institution: | 1. Department of Chemistry, Faculty of Science and Letters, Namik Kemal University, 59860 Tekirdag, Turkey;2. Department of Physiology, Faculty of Medicine, Trakya University, 22030 Edirne, Turkey |
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| Abstract: | A new biflavone, 6,2′,3″,5″,4?-pentahydroxy-3,7″-biflavone, has been isolated from the fruits of Solanum dulcamara L., in addition to two known compounds, β-sitosterol and stigmasterol. Their structures were established on the basis of UV, IR, 1D, 2D NMR and HR-ESI-MS spectroscopic methods. The anti-hyperglycaemic effect of S. dulcamara was investigated using diabetic rats. The anti-hyperglycaemic activity of the fruit extract of S. dulcamara was presented for the first time in this study. |
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| Keywords: | Solonaceae Solanum dulcamara biflavonoid anti-hyperglycaemic activity |
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