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基于改进U-Net++的CT影像肺结节分割算法
引用本文:黄鸿,吕容飞,陶俊利,李远,张久权. 基于改进U-Net++的CT影像肺结节分割算法[J]. 光子学报, 2021, 50(2): 65-75
作者姓名:黄鸿  吕容飞  陶俊利  李远  张久权
作者单位:重庆大学 光电技术与系统教育部重点实验室,重庆 400044;重庆大学附属肿瘤医院 影像科,重庆 400030
基金项目:国家自然科学基金(No.42071302);重庆市基础与前沿研究计划(No.cstc2018jcyjAX0093);重庆市留学人员回国创业创新支持计划(No.cx2019144);重庆市科卫联合项目医学科研项目(No.2019ZDXM007);2019年度中央高校基本科研业务费“医工融合项目”(No.2019CDYGYB008)。
摘    要:卷积神经网络的语义分割模型未有效利用特征权重信息,导致在医学图像复杂场景中分割边界出现欠分割现象.针对该问题,基于融合自适应加权聚合策略提出一种改进的U-Net++网络,并将其应用于电子计算机断层扫描影像肺结节分割.该模型首先在卷积神经网络中提取出不同深度特征语义级别的信息,再结合权重聚合模块,自适应地学习各层特征的权...

关 键 词:计算机图象处理  分割算法  权重聚合  肺结节  CT影像

Segmentation of Lung Nodules in CT Images Using Improved U-Net++
HUANG Hong,LÜ Rongfei,TAO Junli,LI Yuan,ZHANG Jiuquan. Segmentation of Lung Nodules in CT Images Using Improved U-Net++[J]. Acta Photonica Sinica, 2021, 50(2): 65-75
Authors:HUANG Hong  LÜ Rongfei  TAO Junli  LI Yuan  ZHANG Jiuquan
Affiliation:(Key Laboratory of Optoelectronic Technique System of the Ministry of Education,Chongqing University,Chongqing 400044,China;Department of Radiology,Chongqing University Cancer Hospital&Chongqing Cancer Institute&Chongqing Cancer Hospital,Chongqing 400030,China)
Abstract:Convolutional neural network-based semantic segmentation models do not effectively explore feature weight information,which will result in under-segmentation of segmentation boundaries in complex scenes of computed tomography images.To address this problem,an improved U-Net++model is proposed to explore adaptive weighted aggregation strategy based on U-Net++,and the improved UNet++model is applied to the segmentation of lung nodules in computed tomography images.In the convolutional neural network phase,the information from the different levels of deep features is extracted and combined with the weighted aggregation module,and thus the weights of features in each layer are adaptively learned.Then the learned weights are loaded on each feature layer and obtained a sampled segmentation map,and the final segmentation result can be obtained.Segmentation experiments are carried out on the lung cancer data sets of LIDC and Chongqing University Cancer Hospital.The intersection over union of the proposed improved U-Net++method on two datasets reach 80.59%and 87.40%,and the DICE of this method on two datasets could reach 88.23%and 90.83%,respectively.Compared with UNet and U-Net++,the proposed algorithm significantly improves the segmentation performance of lung nodules in computed tomography images.The experimental results show that improved U-Net++achieves accurate segmentation on tiny details of tumors,and it bring beneifits to solve the problem of under segmentation when lung nodules grow invasively to the surrounding.
Keywords:Computer image processing  Segmentation algorithm  Weighted aggregation  Lung nodule  CT image
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